PERIOSTAT is a generic term for a broad spectrum antibacterial agent. The drug used is Doxycycline Hyclate. It belongs to the ‘tetracycline’ class of antibiotics. Patients Buy PERIOSTAT Online which is used in patients with gum disease (periodontitis) after a certain dental procedure like scaling and root planing. The drug is available in form of capsules having 20mg (Doxycycline Hyclate equivalent) for oral administration. This is the first FDA approved the systemic drug, which is used for host modulation as an adjunct to scaling and root planing in the treatment of periodontitis.
When patients buy PERIOSTAT online, the drug is available as film-coated tablets in 20 mg (Doxycycline equivalent) strengths. At this low dosage, PERIOSTAT does not treat bacterial infections, but it may help preventing the breakdown of gum tissues.
Mechanism of action:
PERIOSTAT is an oral enzyme inhibitor which works by reducing the activity of host-derived enzymes, like collagenase. Collagenase is reported to be associated with the destruction of the periodontal support structures during the progression of adult periodontitis. PERIOSTAT is administered systemically, which offers the additional advantage of being able to treat all the tooth sites at the same time, a whole-mouth approach to the management of the host response. The drug also promotes attachment level gain and reduces pocket depths in patients suffering from periodontitis.
Possible Side effects of PERIOSTAT:
Patients can purchase PERIOSTAT online, however; they should understand the possible adverse reactions which may be caused due to it. The following symptoms could be observed due to the administration of Doxycycline Hyclate.
Nausea, vomiting, stomach upset and diarrhoea may be observed in some patients. Urinating less than normal or no urination at all, difficulty in swallowing, headache, rash, itching, swelling, severe dizziness or heartburn are some other symptoms which one may observe while taking PERIOSTAT. If any of these reactions are observed, one should consult his physician. Self-medication is not advised as it may worsen the situation.
Before the patients buy PERIOSTAT online, they must tell their physician about any allergy to other tetracyclines including PERIOSTAT.
Drug interactions and precautions:
Patients buy PERIOSTAT online as per their physician’s direction, but they should disclose their other medications they are taking at the same time. This avoids any significant drug interaction or encourages any alteration in doses of any medication if required.
PERIOSTAT belongs to tetracycline which affects the function of anticoagulants. Therefore patients, who are taking anticoagulants like warfarin simultaneously, are required to adjust the dose as directed by the physician.
The patients should tell the doctor if they are taking retinoid medications orally like acetretin, isotretinoin or if they are taking seizure medications like carbamazepine, phenobarbital or phenytoin before they place an order for PERIOSTAT online.
One should also avoid excessive exposure to the sun as during the treatment with PERIOSTAT, the skin becomes sensitive to the sun. One can wear protective clothing and use sunscreen lotion to avoid sunburns. If one faces severe itching, burning sensation, swelling or rash then a doctor should be consulted immediately.
If the patient has recently taken or will be taking a live oral typhoid vaccine or oral contraceptive then he should avoid the use of PERIOSTAT as the drug may reduce their efficacy.
Theophylline is also reported to show an adverse reaction when administered concurrently with PERIOSTAT.
While diabetic patients are treated with PERIOSTAT, the risk of the side effects of anti-diabetic agents may get increased due to PERIOSTAT.
PERIOSTAT must not be used in children younger than 8 years of age. Similarly, the use should be restricted or avoided under a physician’s guidance in case of pregnancy and breastfeeding.