LEVAQUIN is a synthetic broad spectrum antibiotic Levofloxacin which can be administered orally against bacterial infection. LEVAQUIN is used to treat bacterial infections like pneumonia, acute sinus infection, acute chronic bronchitis (worsening), complicated/uncomplicated skin infections, acute pyelonephritis (kidney infection), inhalational anthrax and plague. Patients Buy LEVAQUIN Online, which is frequently used to treat urinary infections as well as infection of the prostate gland. It belongs to ‘Fluroquinolone’ class of antibiotics. The drug is also effective in treating diarrhoea caused by E.coli, Campylobacter jejuni, Shigella. It can also be used to treat various obstetric infections including mastitis (infection of the breast).
Mechanism of action:
Like other fluoroquinolones, LEVAQUIN arrests the multiplication of bacteria by inhibiting the reproduction and repair of their DNA (genetic material). The bactericidal action of LEVAQUIN results from inhibition of topoisomerase II (DNA gyrase) and IV which are required for bacterial DNA replication, repair, recombination and transcription.
Possible side effects of LEVAQUIN:
Patients buy LEVAQUIN online as prescribed by their physician. However, they should know the possible side-effects of the drug. The reported symptoms as side effects of LEVAQUIN are vomiting, nausea, diarrhoea, headache, constipation, along with less common symptoms like dizziness, abdominal pain, itching, rash with rare allergic reactions like hives (articaria) and anaphylaxis (shock)
There are some serious side-effects like tendon rupture or swelling of tendons (tendinitis). The risk of getting tendon problems while one is taking LEVAQUIN is higher in patients over 60 years of age, in patients taking steroids (corticosteroids) and people having kidney, heart or lung transplant.
LEVAQUIN may also worsen Myasthenia gravis ( a fluoroquinolone problem that causes weakness of muscle) which includes symptoms like difficulty in breathing.
Patients should also inform their Physicians about any hypersensitive fluoroquinolone or other antibiotic before they buy LEVAQUIN online.
It is been reported that LEVAQUIN induces severe hepatotoxicity. Therefore patients should immediately inform the physician if they suffer from any symptoms of liver injury like nausea, vomiting or loss of appetite.
Concurrent administration of LEVAQUIN (tablets or oral solution) along with antacids containing magnesium, aluminium, sucralfate or iron and multivitamins products containing zinc may result in low gastrointestinal absorption of LEVAQUIN. Thus, it shows systemic levels of LEVAQUIN lower than desired.
Research has shown that concurrent administration of LEVAQUIN with anti-coagulant agents like warfarin has enhanced the effect of warfarin.
While diabetic patients are treated with LEVAQUIN, a disturbed blood glucose level is observed when LEVAQUIN is simultaneously administered with an anti-diabetic agent.
Concurrent administration of LEVAQUIN and non-steroidal anti-inflammatory may enhance the risk of CNS (central nervous system) stimulation and convulsive seizures.
Theophylline is also reported to show an adverse reaction when administered concurrently with LEVAQUIN.
Description of dosage forms with excipients:
Patients purchase LEVAQUIN online and they get the drug in three forms: oral tablets, oral solution and injection
LEVAQUIN tablets are film-coated tablets of 250mg, 500mg and 750 mg (Levofloxacin equivalent) strengths. They contain other inactive ingredients like Crospovidone, Hypromellose, Magnesium stearate, Microcrystalline cellulose, Polyethylene glycol, Polysorbate 80, Iron oxide (synthetic red) and Titanium dioxide.
LEVAQUIN oral solution is a multi-use self-preserving aqueous solution of strength 25 mg/ml of Levofloxacin with pH ranging from 5 to6. The colour or appearance of the oral solution may range from clear yellow to greenish yellow. But that does not have any adverse effect on the potency of the drug.
The oral solution contains inactive solution like artificial or natural flavours, ascorbic acid, caramel colour, benzyl alcohol, glycerine, hydrochloric acid, propylene glycol, purified water, sucralose, sucrose and sodium hydroxide (for pH adjustment)
LEVAQUIN injection premix in the single use flexible container is a sterile, preservative-free aqueous solution of Levofloxacin with pH 3.8 to 5.8. It is a dilute, non-pyrogenic, mostly isotonic premixed solution having Levofloxacin in 5% Dextrose. Hydrochloric acid solution or sodium hydroxide solutions may be added to adjust pH.